WildGem is a find and replace program, but it incorporates many special features such as wildcard characters to make it much more powerful than the variety found in your standard text editor. Many people find they don't have time to get into Regex, so WildGem allows most of the versatility of Regex, but without all the confusion.
WildGem focuses on the input and output panes without cluttering up the interface with unnecessary controls. Its special syntax is more memorable than Regex, and it allows you to directly paste text without worrying about escaping characters. Unlike similar programs, WildGem is fast with a dual split display, and updates or highlights matches as you type in realtime.